Rilpivirine Inhibits Drug Transporters ABCB1, SLC22A1, and SLC22A2In Vitro
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منابع مشابه
Rilpivirine inhibits drug transporters ABCB1, SLC22A1, and SLC22A2 in vitro.
Rilpivirine is a nonnucleoside reverse transcriptase inhibitor approved for treatment of HIV-1 infection in antiretroviral-naive adult patients. Potential interactions with drug transporters have not been fully investigated. Transport by and inhibition of drug transporters by rilpivirine were analyzed to further understand the mechanisms governing rilpivirine exposure and determine the potentia...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2013
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01421-13